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Vol. 3 No. 5 (2023)

Alveolar-Arterial Oxygen Gradient Ratio (GAaO2) As A Predictor of Early Mechanical Ventilation In A Patient with Suspected Sars Cov-2 Infection in the Adult Continuous Admission Area of The "Dr. Gaudencio González Garza” Of The La Raza National Medical Center.

Clinical Medicine And Health Research Journal, Vol. 3 No. 5 (2023), 4 October 2023 , Page 585-590
https://doi.org/10.18535/cmhrj.v3i5.248

Abstract

Background: Viruses and mainly COVID and the pneumonia it causes are among the pathologies that cause the greatest damage to the alveolus-capillary membrane of the lungs in patients with this disease.


Objectives: To relate the alveolar arterial oxygen gradient (GAaO2) and the start of early mechanical ventilation in patients with SARS COV - 2 virus infection in the continuous admission area.


Methodology: Descriptive, retrospective, observational, cross-sectional, with 165 clinical records of patients admitted to the emergency area in a period from April 2020 to 2021. Kolmogorov – Smirnov test, Mann-Whitney U and Pearson correlation coefficient were performed. with p>0.05, ROC curve for sensitivity and specificity with Youden index and multivariable regression analysis for correlation.


Results: A cut-off point of GAaO2 = 210.25 was obtained with sensitivity of 95% and specificity of 94%, with 2 times more risk of starting mechanical ventilation and correlation of 89%.


Conclusion: It was observed that the cut-off point was related to greater risk and correlation of initiation of mechanical ventilation. This is a reliable value to decide the start of invasive ventilation.

Keywords:
  • SARS COV-2, arterial blood gas analysis, alveolar arterial oxygen gradient, mechanical ventilation, comorbidities

How to Cite

Moreno López, P. ., Basurto, J. C. ., Luz Rivera Guevara, M. de la ., López, C. V. ., & Mendez de Jesus, I. A. . (2023). Alveolar-Arterial Oxygen Gradient Ratio (GAaO2) As A Predictor of Early Mechanical Ventilation In A Patient with Suspected Sars Cov-2 Infection in the Adult Continuous Admission Area of The "Dr. Gaudencio González Garza” Of The La Raza National Medical Center. Clinical Medicine And Health Research Journal, 3(5), 585–590. https://doi.org/10.18535/cmhrj.v3i5.248

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References

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