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Vol. 3 No. 5 (2023)

Serum Lipid Profile İn Children with Thalassemia Major: A Study On 184 Cases

Clinical Medicine And Health Research Journal, Vol. 3 No. 5 (2023), 2 September 2023 , Page 519-521
https://doi.org/10.18535/cmhrj.v3i5.220

Abstract

Background: Patients with thalassemia major are at risk of developing abnormal lipid profiles.


Aim: In this study, the relationship between iron accumulation and blood lipid profile in TM children was evaluated.


Methods: In this study, blood hemoglobin, ferritin, and lipid levels of pediatric patients with TM aged 1-18 years were investigated. Those with other chronic diseases were excluded from the study.


Results: The median age of 184 patients included in the study was 8 (range 1-18), and 96 (52.2%) of the patients were girls. There is an inverse and statistically significant relationship between age and total cholesterol (TC) level (p<0.05) and age and low-density lipoprotein cholesterol (LDL-C) level (p<0.05). There was an inverse, and statistically significant correlation between ferritin- high-density lipoprotein cholesterol (HDL-C) levels (p:0.015).


Conclusion: As ferritin levels increase in children with thalassemia, HDL-C levels decrease. For cardiac iron accumulation, HDL-C level may be a guide instead of ferritin.

Keywords:
  • Thalassemia major
  • lipid profile
  • total cholesterol
  • triglyceride
  • high-density lipoprotein cholesterol
  • low-density lipoprotein cholesterol

How to Cite

TERZİ, ÖZLEM . (2023). Serum Lipid Profile İn Children with Thalassemia Major: A Study On 184 Cases. Clinical Medicine And Health Research Journal, 3(5), 519–521. https://doi.org/10.18535/cmhrj.v3i5.220

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