http://cmhrj.com/index.php/cmhrj/issue/feedClinical Medicine And Health Research Journal2025-01-19T02:03:33+00:00Dr. Jim Besnardeditor@cmhrj.comOpen Journal Systems<p><strong>Clinical Medicine and Health Research Journal</strong> <em>(CMHRJ) </em>is a peer reviewed journal dedicated to the latest advancement of clinical medicine. The goal of this journal is to serve as a resource for dissemination of state-of-the-art research and educational material within the field of clinical medicine and health science. <em>CMHRJ </em>aims to promote rapid communication and dialogue among researchers, scientists, and engineers working in the areas of clinical medicine and health research Journal. It is hoped that this journal will prove to be an important factor in raising the standards of discussion, analyses, and evaluations relating to clinical medicine and health science programs. The topics related to this journal include but are not limited to:</p> <p> </p>http://cmhrj.com/index.php/cmhrj/article/view/426The Assessment of Health-Related Quality of Life and Knowledge, Attitudes and Practices of Type 2 Diabetics After Participating in Health Education Programme: A Study in The Local of Vietnam 2024-12-26T06:06:11+00:00Le Ke Nghieplekenghiep@gmail.com<p><strong>Introduction:</strong> The proper awareness and education programme improves patient’s knowledge, while changing attitude, leading good practices and improving health-related quality of life. This study purposes evaluated the health education programme results for type 2 diabetes on the health-related quality of life, knowledge, attitude, and practices.</p> <p><strong>Method:</strong> 85 type 2 diabetes diagnosed over six months and aged 35-65 were included the study. Vietnamese Diabetes Quality of Life and Knowledge, Attitude, and Practices questionnaires were used to assess the health-related quality of life and knowledge, attitude, and practices of type 2 diabetes. The education tool was a brochure containing the information diabetes. Descriptive statistics were used for the quantitative data. Qualitative data displayed in numbers and percentages. The changes of the programme results tested by Pair Sample T-test.</p> <p><strong>Results:</strong> 85 patients had an average age of 57.14 ± 6.413 years. All participants had little type 2 diabetic knowledge 37.882 ± 12.639 points. Meanwhile, the patient&#39; s attitude toward disease was average 65.971 ± 19.488 points. However, the patient’s practices were low 52.120 ± 14.150 points. Moreover, their health-related quality of life was low 51.216 ± 19.125 points, however, it improved significantly after 6 months -34.518. Also, there has been significant improvement of the knowledge (6,212), attitude (9.494) and practices (4.771).</p> <p><strong>Conclusion:</strong> The health-related quality of life of type 2 diabetes lowed level, but it changed significantly after participating programme. The patient&#39; s knowledge lowed, the attitude toward disease moderated and the self-care practice lowed, but these problems changed markedly after attending education.</p>2025-01-03T00:00:00+00:00Copyright (c) 2025 Le Ke Nghiephttp://cmhrj.com/index.php/cmhrj/article/view/429Skin-Care Obsessed Kids: The Hidden Risks and Healthy Alternatives Every Parent Should Know2025-01-13T10:34:31+00:00Sabira Arefinpaulisaac513@gmail.comGlobal Health Institute Research Teampaulisaac513@gmail.comDr. Hussam Muhy Abady Al Alwanypaulisaac513@gmail.com<p>The emergence of skincare trends among Generation Alpha has introduced children to beauty regimens at an unprecedentedly young age, largely influenced by social media and adult-targeted marketing. While fostering self-care awareness, this phenomenon raises critical concerns about the safety and appropriateness of such practices for developing skin and overall health. This study investigates the potential health implications of using adult-oriented skincare and cosmetic products, focusing on risks such as hormonal disruptions, allergic reactions, and long-term exposure to harmful ingredients like parabens, phthalates, and formaldehyde. Additionally, the increasing popularity of nail art among children is examined, with attention to the dangers of UV exposure and chemical toxicity. The article advocates for child-friendly, natural alternatives and emphasizes the role of parents, educators, and industry stakeholders in promoting safer practices. By addressing these concerns and fostering sustainable habits, we can protect the health and well-being of future generations while encouraging age-appropriate self-care. </p>2025-01-13T00:00:00+00:00Copyright (c) 2025 Sabira Arefin, Global Health Institute Research Team, Dr. Hussam Muhy Abady Al Alwanyhttp://cmhrj.com/index.php/cmhrj/article/view/425Diagnostic of Fatty Acid Extracted from Peganum Harmala Seed and Effect Study on The Growth the Leishmania Tropica Promastigotes In Vitro2024-12-20T14:23:26+00:00Nahedh Ayad Farisnahedh.a.faris@tu.edu.iq<p>Fatty acids were isolated from the seeds of Peganum harmala, a legume, with petroleum ether. The fatty acids were analyzed using HPLC and were determined to comprise 48.9% Hexadecanoic acid, 2.3% Heptadecanoic acid, 13.7% Octadecanoic acid, and 2.8% Tetradecanoic acid. The current investigation demonstrated that the fatty acids extracted from the seeds of Peganum harmala are more advantageous. The current study's data revealed significant differences p<0.05 across various doses of the petroleum ether oil extract of Peganum harmala and differing exposure durations. The study's findings indicated that the 4 mg/dl dose of the oil extract exhibited the highest inhibitory activity against Leishmania tropica at 24 h 22.50 ± 1.04, 48 h 41.50 ± 1.19, 72 h 64.75 ± 2.66, and 96 h 101.25 ± 0.25. Conversely, the lowest inhibitory dose of 1 mg/dl was recorded at 24 h 66.00 ± 2.20, 48 h 108.75 ± 1.65, 72 h 154.50 ± 1.71, and 96 h 207.00 ± 1.91, in comparison to the control groups 75.25 ± 0.85, 156.00 ± 1.83, 320.00 ± 2.16, 522.50 ± 9.31respectively.</p> <p>Fatty acids exhibited a beneficial effect in suppressing the proliferation of the Leishmaniasis cutanea parasite, namely Leishmania tropica promastigotes, ex vivo.</p> <p>This research presents a possible alternative to pharmaceutical substances, such as streptolyticum, utilized in treating the parasite responsible for cutaneous Leishmaniasis.</p> <p>This study concludes that fatty acids extracted from harmful plant seeds enhance the parasiticidal efficacy with increasing concentration, and prolonged treatment duration correlates with a more significant percentage of parasite elimination.</p>2025-01-24T00:00:00+00:00Copyright (c) 2025 Nahedh Ayad Farishttp://cmhrj.com/index.php/cmhrj/article/view/430Laparoscopic Management of Cholecystoduodenal Fistula Associated with Sclerotic Gallbladder: Case Report2025-01-17T02:12:28+00:00Jonathan E. Quimismunozandradeluis@gmail.comMayling B. Chusanmunozandradeluis@gmail.comJuan R. Molinamunozandradeluis@gmail.comErick H. Zambranomunozandradeluis@gmail.comJose F. Calderónmunozandradeluis@gmail.comGema G. Plazamunozandradeluis@gmail.comLuis A. Muñozmunozandradeluis@gmail.com<p>Cholecystoduodenal fistula (CDF) is a rare and complex complication of chronic cholecystitis and gallstone disease, characterized by an abnormal communication between the gallbladder and duodenum. This report presents the case of a 31-year-old male who presented with right upper quadrant pain, nausea, and jaundice. Imaging studies confirmed a scleroatrophic gallbladder and a CFD. The patient underwent laparoscopic cholecystectomy with partial gallbladder excision, and the fistula was successfully repaired with laparoscopic techniques, including clip application and intracorporeal suturing to invaginate the defect. This case underscores the importance of advanced laparoscopic skills and multidisciplinary approaches in managing complex biliary pathologies.</p>2025-01-25T00:00:00+00:00Copyright (c) 2025 Jonathan E. Quimis, Mayling B. Chusan, Juan R. Molina, Erick H. Zambrano, Jose F. Calderón, Gema G. Plaza, Luis A. Muñozhttp://cmhrj.com/index.php/cmhrj/article/view/432Postoperative Cauda Equina Syndrome: A Report On 10 Patients with Literature Review2025-01-19T02:03:33+00:00T.A. Hamdanalraed77@yahoo.comDarren Luialraed77@yahoo.comAlaa Mohammed Al-baghdadyalraed77@yahoo.comRaed Jasim Chasibalraed77@yahoo.comAli Basim Al-Mahfoodhalraed77@yahoo.comMustafa Habeeb Alshaweealraed77@yahoo.com<p><strong>Background: </strong>Cauda equina syndrome (CES) is a serious condition used to describe the signs and symptoms of patients with compressive neuropathy of multiple lumbar and sacral roots, though in rare cases no compression was discovered, and probably the pathology is related to ischemic changes, this syndrome is well known as an indication for urgent lumbar surgery. It is very rarely seen after surgery, in this study the authors described 10 cases of CES that occurred following uneventful lumbar spine procedures, all had open lumbar decompression.</p> <p><strong>Patients and methods: </strong>Preoperative, operative and post-operative management will be discussed. Special emphasis on the high index of suspicion and the value of MRI as a diagnostic procedure. The age range between 35 to 70 years, six were female and four were males, six had decompression for lumbar canal stenosis, four had CES following lumbar discectomy.</p> <p>Eight had urgent decompression after CES while two were treated conservatively. All presented with cardinal clinical features of CES, in seven patients it was complete while in three patients it was incomplete. The relevant literatures were reviewed.</p> <p><strong>Conclusion: </strong>High index of suspicion is required for early detection of postoperative CES Special surgical technique may reduce the incidence of this syndrome. Wide lumbar decompression or other procedures is urgently required when there is positive MRI findings of compression. Full recovery is not always possible.</p>2025-01-27T00:00:00+00:00Copyright (c) 2025 T.A. Hamdan, Darren Lui, Alaa Mohammed Al-baghdady, Raed Jasim Chasib, Ali Basim Al-Mahfoodh, Mustafa Habeeb Alshawee